[Offer to Sell] Pravastatin Sodium |
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| Name: Pravastatin Sodium QUALITY STANDARD:Compliant with USP, EP and JP CAS Registry Number: 81131-70-6 Molecular Formula: C23H35NaO7 Molecular Mass: 446.52 Chemical Name:(1S-(1-alpha(beta-S*,delta-S*)-2-alpha,6-alpha,8-beta(R*),8a-alpha))-1,2,6,7,8,8a-hexahydro-2-methyl-8-(2-methyl-1-oxobutoxy)-beta,delta,6-trihydroxy-1- Naphthaleneheptanoic acid monosodium salt Appearance: White or off-white crystalline powder Therapeutic Category:Antihyperlipidemic; inhibitor (HMG - CoA reductase) Mechanism of action: HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis. Pravastatin inhibits cholesterol synthesis by reversibly inhibiting HMG-CoA reductase. Pravastatin functions in two aspects: (1) reduces cellular cholesterol synthesis by reversibly inhibiting HMG-CoA reductase activity, so as to increase low density lipoprotein (LDL) receptors, (2) inhibits the prodrug of LDL-- very low density lipoprotein (VLDL) in liver so as to inhibit the synthesis of LDL. |
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